Gene Therapy for a Fevered Planet

Greta ThunbergAt a recent North Bay Bob Dylan tribute, I met a biochemist who manufactured blood proteins to treat hemophilia,.  As we talked, however, she announced that one day her work would go away.  

She explained that blood coagulant requires twelve distinct proteins.  The genomes of hemophiliacs, it turns out, are unable to manufacture number eight.  But it’s now possible to engineer a virus that contains the missing gene sequence.  And if we introduce the virus to hemophiliac bone marrow, the DNA will repair and gain the ability to manufacture the missing protein.  It all sounded miraculous and strange.  

Musicians took up their instruments and the lilting chime of Mr. Tambourine Man filled the room.  

Fifteen months ago, a young Greta Thunberg left school and held a sign outside the Swedish Parliament. She stood alone. Skolstrejk för Klimatet her sign read.  

A year later, millions of young people around the globe struck for climate change. 

In this long hot summer without precedence in human history, it feels indeed as if our planet is burning with fever.  And yet I feel tremendous hope.   I marvel at the mechanisms by which the genome of the body politic can repair itself.  Change does not come just through governmental edict, but can sometimes begin with a single act.  Any small act taken by any one of us. We need not wait to take those small, but necessary and infectious steps — gene therapy, if you will — that will allow our children to have a future.   

We need a system change, rather than individual change, Thunburg said to the body of the UN.

But we cannot have one without the other.

To do your best is no longer enough.

We must all do the seemingly impossible.

Everything needs to change.

And it has to start today.

With a perspective, this is Andrew Lewis

https://www.kqed.org/perspectives/201601139098/gene-therapy-for-the-planet

Remembrance

paratroopersIt was the Day of Days.

On the eve of the invasion, the Allied commander penned a letter in the event of defeat.  “The troops, the air and the Navy did all that bravery and devotion to duty could do,” he wrote. “If any blame or fault attaches to the attempt, it is mine alone.”

Before dawn, 13,000 boys fell out of the sky into the hedgerows of Normandy.  My mother-in-law’s father was among them.  Don Bowman was a radio man in C Company, 501st Regiment, 101st Airborne.  Each by each, the boys flew off the stick into a hail of fire.  One out of five would die that day.  Bowman did not.

There was the Day of Days.

And then there were the days after.  

Bowman’s military records hint at his story.  That year the 101st fought their way across Europe.  Operation Market Garden.  The Ardenne.  Battle of the Bulge.  Liberation of Dachau.  Eagles Nest.  One Purple Heart. A Bronze Star for meritorious valor.

Bullet after bullet.

Medal after medal.

Body after body.

Until victory was had.

But even in victory, the price paid cannot be measured.  In 1969, estranged from his family, alone in Los Angeles, an alcoholic traumatized by war, Don Bowman  purchased himself a cemetery plot.

When asked to list friends or family, he wrote, “None.”

Those boys gave their lives to save Europe.  And now that confederation is being abandoned for want of leadership and the erosive force of nationalist and isolationist fervor.

On this day I think of Don Bowman.

I think that perhaps we owe him more than simple remembrance.

 

Our Burning

OUr Lady WWII

People gathering near the cathedral in August 1944 after Allied forces recaptured Paris.

Why does the burning of Our Lady affect me so?

I’m not a practicing Catholic or even a Christian really.  So why should this conflagration matter?

Although I am not of Christian faith, Christian tropes do apply here.

The Notre Dame Cathedral was designed in the form of a cross, and the bell towers stand at the position of Christ’s feet when he was brutally nailed to that Tree of Life.

The spire once rose directly above the center of the architectural crucifix – that ashen vehicle of sacrifice – and when the spire burned and fell, it pierced the nave like a spear piercing the heart, not of Christ, but of the Christ.

And like the original crucifixion was so intended, this sacrifice may perhaps have shaken us again from a slumber.

When the great teacher and expositor of belief Joseph Campbell was once asked where he prayed, he answered simply, “Notre Dame,”  Our Lady.   Even if he had not been there in years, he explained, her profound space was still his spiritual home.

But the sorrow over her burning is not about denomination. Nor is it necessarily about Christianity or Islam or any other belief system.  The burning matters not so much because it is even a religious thing.

It matters because it is a human thing.

It matters because for many it was a place of secular pilgrimage.  How many of us have taken pictures of ourselves with family or a fiancé there among the gargoyles and demons, as if to say, we one day will die, but here, if just for a moment, we once lived and we once loved.

It matters because Notre Dame is the symbolic center of France (and you could even argue modern Europe and in general the West) – Ground Zero if you will – from which all distances are measured.

And the center – in a time in which the center struggles to hold – matters.

In his recent book, The Road to Unfreedom, Yale historian Timothy Snyder documents how in a highly calculated way foreign actors have worked to undermine political and social cohesion in the United States and in Europe.  A third of Brexit twitter posts were generated by bots as part of a covert Russian media and troll campaign.  The same forces have launched sophisticated social media campaigns in the Ukraine, Hungary, Poland, France, and the US intended to invalidate liberal democracies. Deliberate untruths foment social divisions, including the Yellow Vest movement that has torn apart Paris.

But this is not just about one nation’s imperatives pitted against another.  It concerns an assault on truth itself.  We are being incited to let ourselves be governed by emotion and impulse, by vague belief in what we wish to be true and not in facts themselves.

As our fears are stoked, the spectres of authoritarian governments have risen across Europe and within the United States. Authoritarian leaders do not necessarily seize power.  Afraid, we willingly give it up.

In this strange world, fact and truth are denigrated. Chaos becomes the brand, disintegration the goal.  By turning us against each other, more can be accomplished than through a multitude of guns.   

As our passions become inflamed, the centre cannot hold.

And without a moral or spiritual or truth-bound center, unhealthy impulses grow to fill the void. We frame anyone beyond our immediate tribe as outsiders to be either vilified or feared or destroyed. We turn our selves away from one other.

It took 183 years to build Notre Dame, slightly less time than the United States itself has even existed.  Our Lady represents the greatest of human endeavors – that painstaking and collaborative work that contributes in some small way to a great edifice beyond our own cognition.  Something so vast in conception that in Our Lady’s first construction, neither the first stone masons nor their children nor their grandchildren would ever live to see her completion.

She is about honoring something greater than one’s self.

Call it the perfection of democracy.  Or human emancipation, or equality, or the extension of universal rights to all forms of life, or the prevailing of truth over momentary whim or lies or fancy.

So, strangely then, her burning may now promote a different kind of faith.  Not necessarily in God, but perhaps in us.  Not the us vs. them, but the very center that is simply the collective and embracing us.

For decades the foundation dedicated to preserving Notre Dame struggled to raise funds.  But in the hours after the fires were extinguished, more than 600 million euros poured in from donations both quite large and incomparably small.  We donate because, perhaps, we’ve been awakened to the thought that the center must indeed hold.

Her burning matters because it reminds us of the profound need to come together in a time when individuals and forces are doing all that they can to drive us apart.

burning

Asylum

Rūta. Arija. Ieviņš.

That was my mother’s name.

As a 14 year old girl she travelled on foot the breadth of Europe fleeing the advancing Soviet troops. If she and her father and brother had not fled their native country, they would have died. Their knowledge of this fate was so certain that they eventually risked death to escape it. And for that, they journeyed on a hard, hard road.

My mother would spend her teen years in displaced persons camps in Germany. For five years she lived in detention. She did not have a country that she could go back to. And neither did she have a new one to which she could belong.

And she was abandoned in more ways than one. Her mother died during the war. In flight as a young girl, she was separated from her father for months at a time. These things took their toll. Later in life she would have a hard time forming attachments. She was prone to depression. As a grown woman, she would have difficulty sleeping. She would cry uncontrollably in the night. She was short of temper. In her bouts of sadness and rage, she could sometimes be violent.

But then again, perhaps she had it easy. In February 1945, as a young girl she joined hundreds of thousands of European refugees as they pressed toward the Elbe river. The Yalta Conference had just concluded, and by word of mouth, she learned where the borders would be drawn. Get across the Elbe, the people told one another. Across the Elbe you will be with the Americans.

My mother and brother were instructed to make peace with the American soldiers when they arrived. They were told to just surrender. If nothing else, at least you will get fed, people said. That was quite often the sentiment, my uncle once recalled. You will get fed and you will be taken care of.

Because the Americans don’t mistreat their prisoners.

They are not the Russians.

Rupmaize (the radio version)

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Thank you for the KQED listen.

Rupmaize

Bread, the very symbol of daily sustenance across time and cultures. And to Andrew Lewis and his World War II surviving family members a special bread has special meaning.

As a last act before a recent move, I baked two loaves of rupmaize.

It’s basically a Latvian rye bread – but it’s much more than that, partly because it’s much less. It’s essentially rye flour, water, a little yeast, and some sort of yogurt or kefir (call it turned milk). Mix it up, let the yeasts start to do their thing and then throw in a warm box (call it an oven) to arrest the action. You end up with these loaves that are some crazy cross between that hearty bread eaten by dwarves and that ethereal cake of which elves partake. It’s both sweet and sour. And it sustains.

During World War II, when Latvian families were loading up their wagons preparing for evacuation, no doubt women all over the countryside were hastily wrapping still warm rupmaize in cloth and packing it in baskets. It’s powerful stuff: One slice in the morning and you’re good until mid-day when a second slice keeps you going until afternoon. It can keep you fed when you may not have access to a kitchen for days or months on end.

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The year I lived in Cleveland with my aunt and uncle, my uncle would end the day with a slice of rupmaize and some tea. As part of his ornate ritual, he would fill a ceramic mug with deep black tea and would slowly lather a slice of rupmaize with butter and honey. This was his dessert. He was very particular in the details and I remember him once giggling as he explained them to me. But I was only twelve and I didn’t get it.

For my uncle, a survivor of war and tragedy, this was sacrament. Literally, give us this day our daily bread. As if to say, this stuff is the staff of life. We deserve no more, and just this is enough. A little bit will carry us in a time of need.

And we all have, in every moment, a time of need.